The Last One” marked the end of a long period of dominance for NBC, and a long and humiliating decade to come. NBC would finish the 2003-04 season as the top-rated network among adults 18-49, a crown it had held for pretty much all of the Must-See TV era highlighted by “Friends,” “ER,” “Seinfeld,” et al. Though “ER” would stick around for another five seasons, it was “Friends” that was basically keeping the network afloat, because Jeff Zucker was incapable of developing new hits to replace the aging ones, and therefore his only move was to keep paying David Schwimmer and company small fortunes to stick around as long as possible. “Friends” went away, “American Idol” pushed FOX to the top, and this season (thanks to the Olympics, Sunday football, “The Blacklist” and “The Voice”) will be the first one since then to be won by NBC. (Of course, that fallow period also made long runs possible for otherwise-cancellable shows like “30 Rock,” “Parks and Recreation,” “Friday Night Lights,” “Chuck” and “Community,” so there’s that.)

Four of the six friends have headlined TV shows since then — Matthew Perry alone has done “Studio 60,” “Mr. Sunshine (Yay)” and “Go On,” plus an “Odd Couple” remake in contention for next season — and David Schwimmer finally did a pilot this year. Jennifer Aniston’s still making movies and appearing on supermarket tabloid covers, but I imagine her return to sitcom-dom is coming within the next few years. Given how hard it is to star in one hit TV show, let alone multiples, it’s not surprising that Courteney Cox’s “Cougar Town” is the only one to have a particularly long run, but the “Friends” keep working when they want to. (Yesterday, HBO even announced plans to revive Lisa Kudrow’s “The Comeback.”)

This is one sad day today which makes me remind that F.R.I.E.N.D.S. are gone and it’s been 10 years. There will be no show like F.R.I.E.N.D.S. ever simply because the timing and the chemistry between the six of them is unparalleled.

Who will want to see just one new episode from F.R.I.E.N.D.S.?